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Spire is a software polyphonic synthesizer that combines powerful sound engine. it was released on 20 March 2015, in the form of a free VST plugin under the Reveal .# Project-wide Gradle settings.
# IDE (e.g. Android Studio) users:
# Gradle settings configured through the IDE *will override*
# any settings specified in this file.
# For more details on how to configure your build environment visit
#
# Specifies the JVM arguments used for the daemon process.
# The setting is particularly useful for tweaking memory settings.
org.gradle.jvmargs=-Xmx1536m
# When configured, Gradle will run in incubating parallel mode.
# This option should only be used with decoupled projects. More details, visit
#
# org.gradle.parallel=true
Combined effect of nutrients and endocrine disrupting compounds on functional biomarkers of teleost Gasterosteus aculeatus: lipophilic organic pollutants affect testosterone levels.
Increasing concentrations of endocrine disrupting chemicals (EDCs) are commonly observed in aquatic ecosystems, and have been linked to reproductive malfunction in several fish species. Endocrine disrupting compounds are reported to act through non-genomic and genomic mechanisms. Although many studies focus on how non-genomic endocrine disruption (EGED) of steroidogenesis leads to downstream effects, the impact of endocrine disruption on the enzymatic rates of steroidogenesis is still unknown. To evaluate whether modulation of enzyme activities may be a viable, practical approach for managing pollutant effects, we performed experiments to compare the effect of acute exposure of the acid-sensitive fish Gasterosteus aculeatus to EDC mixtures to the effect of individual EDCs in the presence and absence of nutrient composition typical of industrialized water bodies. Sexually reproducing adult G. aculeatus were exposed to EDCs and nutrients in the
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